It plays a crucial role in facilitating the secretion of cGAS-STING1-dependent type I interferons, which have an important role in the differentiation of both CD8+T cells, CD4+T cells and NK+ cells, as well as in immune-mediated suppression of tumour growth (Yu P. et al., 2022; Saha et al., 2024). The gene discussed is CD8A; the disease is neoplasm.