30 male Sprague–Dawley rats, aged 11 weeks, were divided into five groups of 6 rats, and used to investigate the effects of T1DM on implant outcomes. Diabetes was induced using a 30 mg/kg dose of Streptozocin to create a model of T1DM, and insulin was administered as the treatment medication. The induction of diabetes occurred before the implant placement, ensuring the condition was established prior to the intervention. This evidence concerns the gene INS and type 1 diabetes mellitus.