This study investigates the correlation between the expression levels of ten genes associated with SUMOylation (HDAC1, HDAC4, HDAC9, PIAS1, PIAS2, RAN, RANBP2, SUMO1, RANGAP1, SUMO1) and overall survival (OS) across various cancer types, as illustrated in Figure 1. Here, SUMO1 is linked to cancer.