We then employed the IPS algorithm to analyze the immunophenotype and found that TSPAN4 was correlated with MHC, EC, SC, CP and AZ immunophenoscore in BLCA, GBMLGG, LUSC and STAD, and with IPS immunophenoscore in GBMLGG and LUSC (Figure 5C). Here, HLA-C is linked to bladder transitional cell carcinoma.