Given that we have demonstrated EGCG's ability to suppress oxidative stress in podocytes, and with substantial evidence highlighting the importance of TXNIP in maintaining cellular redox homeostasis, we hypothesize that EGCG could attenuate oxidative stress and inflammation in podocytes and DKD through the TXNIP/NLRP3/IL‐1β axis. This evidence concerns the gene IL1B and diabetic kidney disease.