TNF and Cirrhosis: The tumor necrosis factor (TNF‐α), interleukin‐1 β (IL‐1 β), and interleukin‐6 are pro‐inflammatory cytokines that can enhance the progression of cirrhosis through modulation of various cellular processes including lipid metabolism, biliary system obstruction, positive and negative acute phase proteins, and cirrhosis progression (Slautin et al. 2023).