Numerous studies have confirmed ability of natural products and their derivatives to cure Alzheimer's disease via inhibiting the enzymes (AChE and BChE); for instance, the essential oil obtained from C. officinalis, Origanum syriacum, and Salvia lavandulaefolia have been reported to exhibit considerable anticholinesterase activity in previous investigation (Ak et al. 2021; Loizzo et al. 2009; Perry et al. 2000); furthermore, in previous investigation, the phenolic compounds have been documented as effective inhibitors of both AChE and BChE enzymes (Roseiro, Rauter, and Serralheiro 2012). The gene discussed is BCHE; the disease is early-onset autosomal dominant Alzheimer disease.