TGFB1 and pemphigus foliaceus: Consistent with studies reporting enhanced Wnt/β-catenin signaling in PF models, our results demonstrate that BLM-induced animal models (in vivo) and TGF-β-induced models (in vitro) had elevated Wnt/β-catenin signaling, which was mitigated in PCSK9 inhibitor-treated groups.