IDH1 and neoplasm: One study investigated the relationship between executive function, memory, and psychomotor speed and the intratumoral expression of several markers in untreated patients with diffuse glioma; after correction of tumor volume and location, significant associations were found between psychomotor speed and expression levels of CD3 and IDH-1; memory performance and IDH-1, ATRX, NLGN3, BDNF, CK2Beta, EAAT1, GAT-3, and SRF expression; and executive functioning and IDH-1, P-STAT5b, NLGN3, CK2Beta.