OTULIN and osteosarcoma: To explore the effect of OTULIN expression on the survival of patients with tumors, we extracted data from the TCGA database on OTULIN associated with sarcoma (data on osteosarcoma were not used because there is more abundant data on sarcoma than osteosarcoma) and found that high OTULIN expression significantly reduced the survival of patients with sarcoma (Fig. 1a).