CEBPB and infection: Finally, in zebrafish, C/EBPβ signaling induced during infection with Staphylococcus enterica or overexpression of ectopic C/EBPβ in naïve HSPCs is sufficient to drive this hematopoietic program and produce neutrophils with similarly enhanced bactericidal activity (79) all suggesting that C/EBPβ is an essential mediator of IIM in HSPCs.