UBAP2L-deficiency syndrome, also known as neurodevelopmental disorder with impaired language, behavioral abnormalities, and dysmorphic facies (NEDLBF, OMIM 620494), is caused by heterozygous loss-of-function variants in the UBAP2L gene, located at 1q21.3 (Jia et al., 2022). Here, UBAP2L is linked to neurodevelopmental disorder.