UBAP2L and Delayed speech and language development: A recent study found that variants in the UBAP2L gene were associated with developmental delay (DD), speech delay, mild-to-severe intellectual disability (ID), feeding difficulties in infants, seizures, motor delay, various behavioral abnormalities, hypotonia, skeletal anomalies, facial dysmorphism, and other variable clinical features (Jia et al., 2022) (Figure 1A).