CD4 and androgen insensitivity syndrome: As shown in Figure 4 and Supplementary File 2, the percentage of CD45RA+CCR7+ in CD4+ (naïve CD4+) T cells decreased (Figure 4A, p < 0.01), while the percentage of CD45RO+CCR7+ (Tcm, Figure 4B, p < 0.001) and CD45RO+CCR7− (Tem, Figure 4B, p < 0.001) in CD4+ T cells increased in LVO group as compared with SVO and control groups, suggesting a decrease in naïve CD4+ T cells and an increase in Tcm and Tem CD4+ T cells after AIS with LVO.