FLNC and familial dilated cardiomyopathy: Additionally, mutations in the Lamin A/C (LMNA) gene are associated with an increased risk of sudden cardiac death [9], mutations in the myosin heavy chain (MYH7) gene are linked to early onset and pronounced phenotypic expression [10], and truncation mutations in the Filamin C (FLNC) gene lead to haploinsufficiency, associated with both DCM and arrhythmias [11].