In the ongoing quest for novel therapeutic strategies against GC, researchers are exploring a diverse array of compounds and mechanisms that target various aspects of cancer cell behavior, such as the induced differentiation properties of retinoic acid derivatives, the epigenetic regulation of differentiation by LSD1 inhibition, the antimicrobial potential of tachyzoin, and the redifferentiation role of vitamin c. Here, KDM1A is linked to gastric cancer.