DUSP1 and obesity due to melanocortin 4 receptor deficiency: After taking the intersect, 1 gene was identified to be significantly differentially expressed in both datasets; the gene encoding dual specificity protein phosphatase 1 (DUSP1) was highly induced by both obesity and LDL (W/O vs. WO/O, logFC = 2.91, P = 0.00002 and control vs. LDL, logFC = 0.67, P = 0.0002).