We previously demonstrated that our dTAG molecules known as dTAGV-1 and dTAG-13, which recruit von Hippel-Lindau (VHL) or cereblon (CRBN), respectively, are selective and degrade KRASG12V in several cellular models, including pancreatic ductal adenocarcinoma cell lines (27, 28). Here, VHL is linked to pancreatic ductal adenocarcinoma.