Of note, in the first two days after injection, both empty vector and PDLIM2-expression plasmids were also detected at high levels in those tissues but quickly cleared afterward (data not shown), consistent with the well-documented tumor-specific enrichment of nanoparticles (Yang et al., 2013; Commisso et al., 2013; Huang et al., 2017; Shi et al., 2017). The gene discussed is PDLIM2; the disease is neoplasm.