Similarly, Musashi-2 (MSI2) enhanced high mobility group box 1 (HMGB1) translation by binding directly to nucleotides 1403–1409 of HMGB1 3'-UTR, promoting dendritic cells (DCs) maturation, migration, and the infiltration of CD4+ and CD8+ T cells, which boosted immune infiltration in CRC [43]. This evidence concerns the gene HMGB1 and colorectal carcinoma.