Further studies showed that LINC00207 upregulated HIGD1A via the microRNA-761-HIGD1A axis, activating GSH, reducing hepatic ROS levels, and alleviating oxidative stress-induced hepatocyte damage (Zhang H. et al., 2023).Recent research compared serum lncRNA levels between NAFLD patients and healthy controls, revealing significantly elevated lncRNA MALAT1 levels in NAFLD patients. Here, MALAT1 is linked to metabolic dysfunction-associated steatotic liver disease.