SLC12A1 and hypertensive disorder: Micro-perfusion experiments in Dahl Salt-sensitive rats (Dahl SS) show enhanced absorption by the TAL exclusively (Kirchner, 1990; Hawk and Schafer, 1991; Kirchner et al., 1995; García et al., 1999; Ares et al., 2012) reported that NKCC2 phosphorylation at T96,101 is increased 5-fold in Dahl SS compared to salt-resistant rats on a regular salt diet (Roman and Kaldunski, 1991), and this was independent of the hypertension observed in these rats during high salt.