The secretion of TGF-β by CAFs upregulates the expression of specific LncRNAs—HOTAIR in breast cancer (64), ZEB2NAT in bladder cancer (65), TGILR in gastric cancer (59), and CASC9 in cervical cancer (66)—thus facilitating the metastatic spread of tumor cells. The gene discussed is TGFB1; the disease is urinary bladder carcinoma.