Ro/e preference plots combined with box line plots showed that C6 AVIL+ TCs preferred the G2M phase, while C1 APCDD1+ TCs preferred the S phase, and were favored by adenoma tissues, whereas in contrast, C2 MUC2+ TCs, C4 OTOP2+ TCs, and C5 SLC26A3+ TCs were found overwhelmingly in the normal tissue and para-cancer tissues, whereas C0 FXYD5+ TCs preferred carcinoma tissues (Figures 2B, C). This evidence concerns the gene OTOP2 and adenoma.