TNF and neoplasm: CD137+ TRTs from all three samples showed considerably increased production of IFN-γ (p=0.0858, n=3) and TNF-α (p=0.0661, n=3) as well as upregulation of CD107a (p=0.0692, n=3) and CD137 (p=0.0836, n=3) upon co-culture with autologous tumor cell lines (Figure 5A).