ENPP2 and cancer: Through TIMER2.0, we discovered that ENPP2 was associated with the degree of infiltration of Endothelial (Rho = 0.529, p = 1.16e−07), T cell regulatory (Rho = 0.373, p = 3.45e−04), cancer correlated fibroblast cell (Rho = 0.359, p = 2.57e−10), Hematopoietic stem cell_XCELL (Rho = 0.348, p = 8.98e−04), mast cell activated (Rho = 0.355, p = 6.95e−04) (Figs. 12A, 12B).