observed that inhibiting glycolysis partially reduced NLRP3 inflammasome activation in acute lung injury (ALI).[41] In this context, we paid attention to the NLRP3 inflammasome and found that MLT‐MLP treatment did reduce the NLRP3 inflammasome activation, accompanied by the reduction of caspase 1 and IL‐1β release. This evidence concerns the gene NLRP3 and acute lung injury.