To identify the upstream molecular of MLLT3, we examined the promoter activity of MLLT3 gene by introducing its promoter from a tumor or normal tissue into pGL3B and found that the promoter activity of the MLLT3 gene in tumor or normal tissue has no difference, indicating the expression of MLLT3 was regulated in a post‐transcription manner in melanoma (Figure3A). Here, MLLT3 is linked to melanoma.