Under strict quality controls (Figure S2, Supporting Information), proteomic analysis of 148 selected tissue samples (BrM, n = 48; BrM‐NAT, n = 16; Glioma, n = 49; Glioma‐NAT, n = 7) yielded a total of 12 808 protein groups, of which 48.13% were phosphorylated (Figure 1D; Figure S3, Supporting Information). Here, BRD2 is linked to central nervous system cancer.