Meanwhile, we noticed that CD8+ MAIT cells exhibit stronger expression of anti‐tumor molecules (IFNG and TNF) in the normal liver tissue and exhibit a gradual decrease in anti‐tumor ability from normal liver tissue to the invasive tumor front, and to core tissue (Figure S3G, Supporting Information), which might be associated with the metabolic change in different regions, noticing the elevated levels of hypoxia and glycolysis activities (Figure S3H, Supporting Information). This evidence concerns the gene IFNG and neoplasm.