COX4I1 and leukemia: For example, it has been studied for its antiemetic properties and potential to enhance chemotherapy's effects in cancer treatment.[24] The anti‐AML capacity of chlorpromazine was also recently identified.[30] Interestingly, chlorpromazine was known to inhibit the mitochondrial Complex IV activity, providing a pharmacological tool that mimics the blocking of COX4I1 in leukemia cells.