Evidence-based studies are representative of altered levels of inflammatory cytokines, including C-reactive protein, IL-1, IL-6, and TNF-α in schizophrenia patients, which affect the basal ganglia and induce negative symptoms (Stojanovic et al., 2014; Goldsmith et al., 2018; Liemburg et al., 2018). The gene discussed is TNF; the disease is schizophrenia.