To enhance the applicability of the KWM/Hym model to human cataracts, it is necessary to investigate variations in cataract-related biomarkers (such as reactive oxygen species, superoxide dismutase, catalase) and mutations in genes (such as Crystallin Alpha A, Crystallin Alpha B) associated with cataract formation, as reported in humans, using the KWM/Hym model. The gene discussed is CRYAB; the disease is cataract.