INS and type 1 diabetes mellitus: Based on the available data, this meta-analysis showed that CGM increased TIR by 7.4% compared to the control, which surpasses the threshold of 5% for clinical significance [61] and is consistent with other meta-analyses, which have shown an increase in TIR by 5.6% from baseline following CGM in individuals with T1DM or T2DM [10], and an increase in TIR by 8.6% compared to SMBG in those with T2DM not using insulin [9].