To further understand the role of KLF1 and TRIM13 in NSCLC, we overexpressed KLF1 in A549 cells by transfecting them with oe-KLF1 (p < 0.01, Fig. 5A, B) and then combined this with RBM15 knockdown using si-RBM15-3. This evidence concerns the gene KLF1 and non-small cell lung carcinoma.