Compared with normal mice (−K/BxN serum −HFD), the levels of G-CSF (P < 0.01), IL-12p40 (P < 0.05), MIP-1β (P < 0.001), MIP-1α (P < 0.01) significantly increased in atherosclerosis mice (-K/BxN serum + HFD) (Fig. 3E). The gene discussed is CCL4; the disease is atherosclerosis.