PVALB and Hip dysplasia: Deletion of Piezo2 in proprioceptive neurons (Pvalb-Cre:Piezo2f/f) but not in osteogenic (Col1a-Cre:Piezo2f/f) or chondrogenic (Col2a-Cre:Piezo2f/f) cells resulted in skeletal defects, including spine malalignment and hip dysplasia [21].