A recent biostatistical analysis study performed on TCGA datasets concerning AMPK (AMP-activated protein kinase) expression patterns in lung cancer, adenocarcinoma, and squamous cell carcinoma, respectively, revealed that AMPKα1 was poorly expressed across all pulmonary neoplasm subtypes, which in turn correlated with a high metastatic potential and a decreased overall survival rate. The gene discussed is PRKAA1; the disease is lung neoplasm.