In this study, we show that the addition of IGFBP2 recombinant protein in our in vitro model of EHT results in the emergence of an increased number of functional haematopoietic progenitors, and we provide an early observation to suggest that RUNX1T1 could be involved in the regulation of its expression. The gene discussed is RUNX1T1; the disease is essential hypertension, genetic.