SIRT1 and infection: During infection of T. gondii, 4-hydroxybenzaldehyde, an aromatic compound, induces SIRT1-mediating autophagy by increasing the intracellular co-localization of autophagic vacuoles and T. gondii-containing parasitophorous vacuoles in bone marrow-derived macrophages, and the SIRT1-mediating autophagy restricts the intracellular propagation of T. gondii (45).