For example, when biochemical studies on RWL were examined, it was reported that RWL causes acute kidney injuries (13), failure to reduce muscle damage markers to basal levels as a metabolic response (21) and extended recovery time (22), increases in plasma osmolarity and ghrelin hormone levels (15), increases in cortisol levels, but decreases in testosterone levels (23). The gene discussed is GHRL; the disease is acute kidney injury.