Although there was no separation across the disease classes on LV2, we found NDUFB1, ATP6V0C, COX7C, COX6C, and CHGA contributed greater than average (VIP > 1) to the control group, whereas ALB, TNRC18, SLC9A1, BNC1, BCORL1, and ZNF467 had a VIP >1 for AD. Here, NDUFB1 is linked to Alzheimer disease.