Research conducted on subarachnoid haemorrhage model mice demonstrated that luteolin was able to repair oxidative damage by increasing the expression of nuclear factor-erythroid 2-related factor 2 (Nrf2) and downregulation of the activation of inflammatory nod-like receptor pyrin domain-containing 3 (NLRP3) [259]. This evidence concerns the gene NFE2L2 and subarachnoid hemorrhage.