Interestingly, that study suggested that LDL(-) triggers ischemic stroke by promoting thrombosis, through the induction of platelet aggregation and hemostasis via lectin-like oxidized LDL receptor-1 (LOX-1) and IκB kinase 2 (IKK2)/nuclear factor–κB (NF-κB) signaling (109). This evidence concerns the gene OLR1 and ischemic stroke.