EPCAM and cancer: Furthermore, TCMs facilitate tumor targeting and adhesion through tumor characteristic functional factors such as Galectin‐3, N‐cadherin, E‐cadherin, and the epithelial cell adhesion molecule (EpCAM).[43] Reportedly, TCMNPs could treat cancer via effective APCs uptake,[44] robust T cell cytotoxicity, and excellent tumor targeting.[45] In recent decades, TCMNP platforms have been greatly enhanced with various membrane sources and a wide range of synthetic nanomaterials, for instance, biodegradable polymers, inorganic materials, and virus particles[32, 46, 47] (Figure 2).