IFNG and neoplasm: The activation of CTLs with increased IFN‐γ production by melanoma TEX‐loaded DCs was first reported by Wolfers et al.[207] Unlike tumor lysates, TEXs contain complete membrane constructions and richer contents, which activate DCs and induce significant CTL cytotoxicity without leading to DC apoptosis.[208, 209, 210, 211] Additionally, TEXs serve as effective agents for DC imaging, and tracking TEXs is easy for DC internalization.[212]