Among them, blocking the supply of glucose by specific metabolic enzymes (e.g., glucose oxidase, GOx) to limit the energy required for tumor cell proliferation has become a promising strategy, as the generated products, H2O2 and gluconic acid, can also be used in combination with other treatment modalities.[212, 213] The photothermal effect and hypoxia relief resulting from PTT and NO gas are beneficial to the decomposition of glucose for ST, as the GOx‐based glycolysis process is O2‐dependent. This evidence concerns the gene HAO1 and neoplasm.