CGAS and cancer: In addition to inorganic compounds, free Mn2+ also coordinates with organic ligands to self‐assemble into nanoscale metal‐phenolic network The CpG‐ODN‐coated Mn‐phenolic networks (CMP) that were self‐assembled by Mn2+, CpG‐ODN, and TA, induced TAMs polarization and cGAS‐STING activation and further synergized with IRE for effective cancer immunotherapy.[32] In this study, the research team demonstrated the effective T1‐weighted MRI performance of the CMP NPs with r1 of 11.64 mm/s, indicating the potential of the CMP NPs for image‐guided therapy.