CD8A and melanoma: Similarly, HLA-A2-restricted p-peptides derived from IRS2 (pIRS21097–1105 (RVApSPTSGV)), β catenin (pβ catenin30–39 (YLDpSGIHSGA)), and CDC25b (pCDC25b38–46 (GLLGpSPVRA)) were recognized by specific CD8+ T lymphocytes in ovarian carcinoma (COV413), and melanoma cell lines (DM331, SLM2) [43].