Tumor necrosis factor (TNF)-α and interleukin (IL)-6 are two representative biomarkers that are closely linked with OSA (Kheirandish-Gozal and Gozal, 2019), and more intriguingly both are also thought to contribute to neurocognitive dysfunction (Tegeler et al., 2016). The gene discussed is IL6; the disease is obstructive sleep apnea syndrome.