In the setting of prolonged PT and PTT, antiphospholipid antibody work-up was initiated, which revealed negative cardiolipin IgA/IgM/IgG, negative beta 2 glycoprotein IgA/IgM/IgG, and positive lupus anticoagulant hexagonal phase phospholipid neutralization. The gene discussed is CD79A; the disease is systemic lupus erythematosus.