a is the number of adverse drug event reports that report pancreatitis associated with TNF inhibitor use, b is the number of reports that report other AEs associated with TNF inhibitor use, c is the number of reports that report pancreatitis associated with other drugs, and d is the number of other AEs (besides pancreatitis) associated with other drugs (besides TNF inhibitors). This evidence concerns the gene TNF and pancreatitis.